Phytochemical Identification and Analgesic Potential of the Seed Extract of Irvingia gabonensis

Different parts of Irvingia gabonensis are used ethno-medicinally in some West Africa culture the treatment pain. The stem bark has been reported literature to possess analgesic property. In order evaluate potential seed extract and phytochemicals that may be responsible for this effect. This study was aimed at determining phytochemical contents effect I. gabonensis. screened using standard procedures GC-MS analysis. It central peripheral potentials were evaluated doses 50 mg/kg, 100 mg/kg 200 acetic acid induced abdominal writhing hot plate methods Swiss albino mice. Acetylsalicylic (100 mg/kg), morphine hydrochloride (2 mg/kg) pentazocine (15 as drugs. ANOVA analyze data from results level significance set P ≤ 0.05. Phytochemical screening showed presence alkaloid, flavonoid, cardiac glycoside, triterpenoid saponin. analysis revealed thirty compounds mostly fatty acids. At methanolic extract, there a dose dependent decrease response which also compared well with acetylsalicylic acid. From results, contains could precieved activity.